The ability to detect AML-specific fusion genes is critical in both clinical and research settings.
The AML Q-Fusion Screening Kit is a novel, multiplex, reverse transcription real-time PCR (RT-qPCR) system able to simultaneously detect 16 fusion genes, including PML-RARα L and PML-RARα S. Fusion and control gene transcripts are co-amplified in each reaction and identified by specific fluorescent probes. The Q-Fusion system provides a sensitive, specific, reliable and cost-effective tool that is easy to perform for the routine screening of leukemia fusion transcripts.
For Research Use Only. Not intended for use in diagnostic procedures
Fusion genes | MLL-AF9, CBFβ-MYH11, PML-RARα L, PML-RARα S, AML1-MDS1, NPM-MLF1, AML1-ETO, NPM-RARα, PLZF-RARα, DEK-CAN, MLL-ELL, AML1-EAP, MLL-AF10, SET-CAN, TEL-ABL1, TLS-ERG, NPM-ALK |
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Sample types | Bone marrow, peripheral blood, FFPE, and cell lines |
Reaction Volume | 25 ul |
Reaction time | 2-3 hour |
Internal control | GUSB as housekeeping genes, 2 positive control, 3 negative control |
Sensitivity | 10-4 |
Instruments | Compatible with Bio-Rad CFX96, iCycler, ABI7500, Stratagene Mx3000P/Mx3005P, and other commonly used RT-qPCR machines. |
Cat. No. | Description | Size |
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1-100-20010 | AML Q-Fusion Screening Kit |
10-reactions |
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