Specific double-stranded probes for homogeneous detection of nucleic acid and their application methods; Patent No. US 7799522; Patent Date: Sep. 21, 2010 – Read More

A new class of homogeneous nucleic acid probes based on specific displacement hybridization. Li Q, Luan G, Guo Q, Liang J., Nucleic Acids Res. 2002 Jan 15;30(2):E5. – Read More

A new fluorescent quantitative polymerase chain reaction technique. Shengqui W, Xiaohong W, Suhong C, Wei G. Anall Biochem 2002;309:206–211. – Read More

Real-time PCR genotyping using displacing probes. Cheng J, Zhang Y, Li Q. Nucleic Acids Res. 2004 Apr 15;32(7):e61. – Read More

Thermodynamically modulated partially double-stranded linear DNA probe design for homogeneous real-time PCR. S. Huang, J. Salituro, N. Tang, K. C. Luk, J. Hackett, P. Swanson,G. Cloherty, W. B. Mak, J. Robinson and K. Abravaya, Nucleic Acids Research, 2007, 35, e101. – Read More

Real-time quantification of RNA polymerase activity using a “broken beacon”. R. H. Blair, E. S. Rosenblum, E. D. Dawson, R. D. Kuchta,L. R. Kuck and K. L. Rowlen, Analytical Biochemistry, 2007, 362,213–220. – Read More

Real-time PCR detection of multiple lamivudine-resistant mutations with displacing probes in a single tube. Wen H, Li Q. J Clin Virol. 2007 Apr;38(4):334-40. Epub 2007 Feb 27. – Read More

Multicolor real-time polymerase chain reaction genotyping of six human platelet antigens using displacing probes. Ruan L, Pei B, Li Q., Transfusion. 2007 Sep;47(9):1637-42. – Read More

Real-time PCR genotyping of aldehyde dehydrogenase-2 using displacing probes. Gu Y, Li Q. Clin Biochem. 2007 Nov;40(16-17):1325-7. Epub 2007 Aug 10. – Read More

A novel universal real-time PCR system using the attached universal duplex probes for quantitative analysis of nucleic acids. Yang L, Wanqi Liang1, Lingxi Jiang, Wenquan Li, Wei Cao, Zoe A Wilson and Dabing Zhang, BMC Molecular Biology 2008, 9:54 – Read More

A double-stranded molecular probe for homogeneous nucleic acid analysis. D. Meserve, Z. Wang, D. D. Zhang and P. K. Wong, Analyst, 2008,133, 1013–1019. – Read More

Hybridization kinetics of double-stranded DNA probes for rapid molecular analysis. Gidwani V, Riahi R, Zhang D, Wong P, Analyst, 2009, 134, 1675-1681 – Read More

Multicolor real-time PCR genotyping of ABO system using displacing probes. Ruan L, Zhao H, Li Q. J Forensic Sci. 2010 Jan;55(1):19-24. Epub 2009 Dec 2. – Read More

Molecular diagnosis and targeted therapy of a pediatric chronic eosinophilic leukemia patient carrying TPM3-PDGFRB fusion. Li Z, Yang R, Zhao J, Yuan R, Lu Q, Li Q, Tse W. Pediatr Blood Cancer. 2011 Mar;56(3):463-6. – Read More

Molecular detection of bacterial pathogens using microparticle enhanced double-stranded DNA probes. R. Riahi, K. E. Mach, R. Mohan, J. C. Liao and P. K. Wong, Anal. Chem., 2011, 83, 6349–6354 – Read More

Optimizing the specificity of nucleic acid hybridization, Zhang D, Chen S, Yin P. Nature Chemistry, 2012, Vol 4, 208-214 – Read More

Robust sequence discrimination, Altan-Bonnet G, Kramer F. Nature Chemistry, 2012, Vol 4, 155-157 – Read More

Detection of mRNA in living cells by double-stranded locked nucleic acid probes. Riahi R, Dean Z, Teitell MA, Chiou PY, Zhang DD, Wong PK. Analyst. 2013 June 17 – Read More

Saliva as a sampling source for the detection of leukemic fusion transcripts. Chen D, Song N, Ni R, Zhao J, Hu J, Lu Q, Li Q. J Transl Med. 2014 Nov 19;12(1):321. – Read More