EML4-ALK Fusion Gene Detection

EML4-ALK Fusion Gene Detection
ELM ALK report 1

A novel, simple, and multiplex test to detect commonly found EML4-ALK subtypes.

Identification of the EML4-ALK fusion gene, which is present in 5-7% of non-small cell lung cancer (NSCLC) cases, has significant implications for therapy selection. Presence of the EML4-ALK gene promotes tumor cell growth, and also indicates poor response to therapies that inhibit EGF receptor (EGFR) activity. In patients carrying the EML4-ALK fusion gene, specific anaplastic lymphoma kinase or ALK inhibitors like Crizotinib have shown promising results.

Diagnostic testing for ALK fusion genes is routine in panel testing for NSCLC. QuanDx’s EML4-ALK fusion gene detection kit provides a simple multiplex test to detect commonly found EML4-ALK subtypes, requiring minimal sample preparation while providing consistent, reliable results.

Key Features:

  • Multiplexing: simultaneous detection of 17 fusion variants.
  • Compatible with current real-time qPCR instruments.
  • Results within 2 hours.
  • Easy to perform for routine screening.
  • Provides consistent, reliable results.

For Research Use Only. Not intended for use in diagnostic procedures.

Product coming soon.

 

Contact Us  :    1-855-QuanDx-Care (1-855-782-6392)   OR   650-262-4140       info@quandx.com     Product Inquiry
Technical Specs
Fusion VariantsV1, V2, V3a/b/c, V4, V5a/b, V6a/b, V7, V8a/b/d, V10
Sample typesFFPE, frozen, and fresh lung cancer tissue
Reaction Volume20 µl
Reaction time2 hours
Internal controlGUSB as housekeeping gene
InstrumentsCompatible with Bio-Rad CFX96, iCycler, ABI7500, Roche Lightcycler 480,  Stratagene Mx3000P/Mx3005P, and other commonly used RT-qPCR instruments.
Ordering Information
Cat. No.DescriptionSize
1-200-10020

EML4-ALK Fusion Gene Detection Kit

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